North Carolina HB 330: Controlled Substances Act - Updates.

Bill Text

GENERAL ASSEMBLY OF NORTH CAROLINA
SESSION 2025
H 2
HOUSE BILL 330
Committee Substitute Favorable 3/18/25

Short Title: Controlled Substances Act - Updates. (Public)
Sponsors:
Referred to:
March 10, 2025
*H330-v-2*
A BILL TO BE ENTITLED 1
AN ACT TO UPDATE THE CONTROLLED SUBSTANCES ACT. 2
The General Assembly of North Carolina enacts: 3
SECTION 1.(a) G.S. 90-89(1) reads as rewritten: 4
"(1) Opiates. – Any of the following opiates or opioids, including the isomers, 5
esters, ethers, salts and salts of isomers, esters, and ethers, unless specifically 6
excepted, or listed in another schedule, whenever the existence of such 7
isomers, esters, ethers, and salts is possible within the specific chemical 8
designation: 9
... 10
sss. AP-237. 11
ttt. 2-methyl AP-237. 12
uuu. (ortho, meta, or para)-methyl AP-237. 13
vvv. AP-238. 14
www. (ortho, meta, or para)-hydroxy 2-methyl AP-237. 15
xxx. 2-Naphthyl U-47700. 16
yyy. 1-Naphthyl U-47700. 17
zzz. 4-(Trifluoromethyl) U-47700. 18
aaaa. Methoxy U-47700. 19
bbbb. Furanyl UF-17. 20
cccc. Cyclopropyl U-47700. 21
dddd. Phenyl U-47700. 22
eeee. Ethyl U-47700. 23
ffff. (2,3- or 3,4)-difluoro-N,N-didesmethyl U-47700. 24
gggg. (2,3- or 3,4)-difluoro U-49900. 25
hhhh. (2,3- or 3,4)-difluoro-N-desmethyl U-47700. 26
iiii. 4-fluoro U-47931E. 27
jjjj. (2,3- or 3,4)-difluoro U-51754. 28
kkkk. (2,3- or 3,4)-difluoro Isopropyl U-47700. 29
llll. (2,3- or 3,4)-difluoro Propyl U-47700. 30
mmmm. (2,3- or 3,4)-difluoro U-50488. 31
nnnn. (2,3- or 3,4)-difluoro U-48800. 32
oooo. (2,3- or 3,4 or 2,4)-difluoro U-47700. 33
pppp. UF-17. 34
qqqq. U-47109. 35
rrrr. U-48520. 36

General Assembly Of North Carolina Session 2025
Page 2 House Bill 330-Second Edition
ssss. N,N-didesmethyl U-47700. 1
tttt. U-62066. 2
uuuu. Propyl U-47700. 3
vvvv. (2,3- or 3,4)-Ethylenedioxy U-51754. 4
wwww. 4-phenyl U-51754. 5
xxxx. N-desmethyl U-47700. 6
yyyy. (2,3- or 3,4)-Ethylenedioxy U-47700. 7
zzzz. N-methyl U-47931E. 8
aaaaa. (2,3- or 3,4)-Methylenedioxy U-47700. 9
bbbbb. U-69593. 10
ccccc. U-50488. 11
ddddd. U-48753E. 12
eeeee. U-47931E." 13
SECTION 1.(b) G.S. 90-89(1a) reads as rewritten: 14
"(1a) Fentanyl derivatives. – Unless specifically excepted, listed in another 15
schedule, or contained within a pharmaceutical product approved by the 16
United States Food and Drug Administration, any compound structurally 17
derived from N-[1-(2-phenylethyl)-4-piperidinyl]-N-phenylpropanamide 18
(Fentanyl) by any substitution on or replacement of the phenethyl group, any 19
substitution on the piperidine ring, any substitution on or replacement of the 20
propanamide group, any substitution on the anilido phenyl group, or any 21
combination of the above unless specifically excepted or listed in another 22
schedule to include their salts, isomers, and salts of isomers. Fentanyl 23
derivatives include, but are not limited to, the following: 24
... 25
f.26
N-(2-fluorophenyl)-N-[1-(2-phenylethyl)-4-piperidinyl]-propana27
mide (also known as 2-fluorofentanyl).(also known as 28
ortho-fluorofentanyl). 29
g.30
N-(3-fluorophenyl)-N-[1-(2-phenylethyl)-4-piperidinyl]-propana31
mide (also known as 3-fluorofentanyl).(also known as 32
meta-fluorofentanyl). 33
... 34
i.35
N-(4-fluorophenyl)-2-methyl-N-[1-(2-phenylethyl)-4-piperidinyl]36
-propanamide (also known as 4-fluoroisobutyryl fentanyl, 37
4-FIBF).(also known as 4-fluoroisobutyryl fentanyl). 38
j. N-(4-fluorophenyl)-N-[1-(2-phenylethyl)-4-piperidinyl]-butanamide 39
(also known as 4-fluorobutyryl fentanyl, 4-FBF).(also known as 40
para-fluorobutyryl fentanyl)." 41
SECTION 1.(c) G.S. 90-89 is amended by adding a new subdivision to read: 42
"(1b) Nitazene derivatives. – The N-substituted benzimidazole structural class, 43
including any of the following derivatives, their salts, isomers, or salts of 44
isomers unless specifically utilized as part of the manufacturing process by a 45
commercial industry of a substance or material not intended for human 46
ingestion or consumption, as a prescription administered under medical 47
supervision, or for research at a recognized institution, whenever the existence 48
of these salts, isomers, or salts of isomers is possible within the specific 49
chemical designation or unless specifically excepted or listed in this or another 50
schedule, structurally derived from benzimidazole by substitution at the 51

General Assembly Of North Carolina Session 2025
House Bill 330-Second Edition Page 3
1-position nitrogen with an ethylamine group, and by substitution at the 1
2-position carbon with a benzyl group, whether or not the compound is further 2
modified in any of the following ways: 3
a. By monoalkyl or dialkyl substitution on the 1'-nitrogen of the 4
1-position ethylamine group, or by inclusion of the nitrogen in a cyclic 5
structure. 6
b. By substitution on the 2'-methylene carbon of the benzyl group by 7
alkyl or carboxamide groups. 8
c. By replacement of the 2'-methylene carbon group with an ethylbenzyl, 9
thiophenol, or methoxybenzene group, whi